Imaging Monday confirmed a PCL sprain for McMillan, who will now move to injured reserve with a 6-8 week recovery timeline. The Buccaneers are also dealing with an injury to quarterback Baker Mayfield’s thumb on his throwing hand, although initial testing was positive. Now sitting at 0-3 and in last place in the NFC South, they’ll likely look to youth to attempt to save their season. On that note, no team in the division currently holds a winning record through three weeks.

It’s hard to write these quotes without sounding “clicky,” but Harbaugh was forthright at his Monday press conference when asked about Herbert’s decision-making. “Be better. Be better,” Harbaugh said before attempting to soften the blow. “And that drives Justin, that drives me, that drives his position coach, that drives (OC Mike [McDaniel). I mean, drives us all.” Harbaugh also said the team could look to simplify McDaniel’s complex scheme. “As far as the scheme going forward, all options are open,” Harbaugh claimed. When asked what that might entail, the coach responded “run, pass, up the middle, motion, no motion.” Alrighty then. It’s shocking to hear a coach talk this frankly — especially Harbaugh about Herbert — but the situation really is that dire in Los Angeles. Herbert is in the crossfire, but it could be McDaniel who is on something of a hot seat with his play-calling. Sitting at 0-3, the Chargers face the unwelcome prospect of a “must win” Week 4 contest against defending Super Bowl champion Seattle, itself coming off a rough loss. We will be benching Herbert in fantasy for that one.

Ferguson briefly departed after injuring his ankle in the team’s Sunday Night Football loss to the Broncos, returning for two snaps prior to departing again after his lone reception of the evening. The ankle injury now appears likely to cost the talented young tight end at least one game, with the potential for the absence to linger if the sprain is “more high than low.” McVay also relayed that fellow tight end Colby Parkinson suffered an AC sprain and is considered day-to-day. Veteran Tyler Higbee would be in line to operate as the primary receiving tight end after amassing 62 yards and a touchdown on eight receptions in Week 3, should both miss. Higbee should be added in all formats as a potential TE1 in the immediate future.

We continue to get very little concrete news from McVay and the Rams regarding the injury, expected status, or recovery timeline for star wide receiver Puka Nacua. The most conclusive information given the previous two weeks is that the groin injury Nacua is dealing with is not related to the psoas injury he dealt with this offseason, although some have speculated that the verbiage used to describe the injury sounded like a sports hernia. Even that is pure speculation. Fantasy managers are left waiting in the holding pattern for more concrete news from their first-round fantasy selection. Davante Adams would clearly be in line to benefit from another absence after setting a career-high in receiving yards in consecutive games the previous two weeks.

Dowdle was unable to play in the team’s Week 3 win over the Bengals with the same issue and will likely need to get back on the practice field to have a chance to suit up on Thursday Night Football against the Browns in Week 4. Expect Jaylen Warren to see another game of workhorse usage after a 90 percent snap rate on Sunday, should Dowdle be unable to go. Warren would be a volume-based RB1 in a middling matchup in Dowdle’s absence.

The season is only three weeks old, but it already feels like Evans has dealt with a whole year’s worth of injuries. The veteran receiver dealt with quad and abductor injuries in training camp and was listed with a hip injury entering Week 3’s game against the Cardinals. Now, he’ll look to play through a rib injury that had him carted off the field in the second quarter of Sunday’s win. It sounds like Evans will have a chance to suit up in Week 4 against the Broncos, but we’ll see how things look when the team releases its first injury report on Wednesday.

The Giants have now lost key starters in back-to-back weeks due to serious knee injuries. Burns will undergo season-ending knee surgery in the coming days and should be ready to go for the start of next season if all goes well. The veteran pass-rusher totaled four tackles this season and failed to record a sack.

Head coach Kevin O’Connell said after Sunday’s game that Jefferson was “close” to returning, so Monday’s report isn’t all too surprising. While Week 4’s game remains on the table for Jefferson, the Vikings could very well opt to sit him this week against a Dolphins offense that’s among the worst in the league and just lost its star player to a torn ACL. Jefferson’s status will be one to monitor throughout the week, but it wouldn’t be surprising if the Vikings rested him for at least one week given the injury and the upcoming matchup.

Quinn also included Chig Okonkwo and LB Frankie Luvu in the group of players who could return to practice this week, depriving us of a little nuance. We wouldn’t go into Week 4 waivers anticipating that Daniels is going to play, but it probably isn’t entirely off the range of outcomes after Sunday’s reporting said he could return in “three weeks or sooner.”

It’s unclear how much time Etienne will miss, but it wouldn’t be surprising if this became an injured reserve stint. Alvin Kamara could find himself in a more elevated role next week, perhaps with Kendre Miller joining him in a committee. Etienne exited Week 3’s loss to the Raiders with the injury after rushing for 57 yards on 13 carries. It had already been a tough scene for Etienne-reliant fantasy managers this year just based on how the results on the field were going; this won’t help.